American Serenade, Mississippi

Mississippi, Arkansas, Escambia, Mobile, Biloxi, Wolf and Pascagoula

Free Internet
Riverview Cabins
Jacuzzi / Hot Tub
En-Suite bathrooms
Family Cabins
Aircon Cabins
Warm Water Showers

from $ 592/ night Check dates

Highlights

Multiple dining venues
Fitness center on board

Step aboard American Serenade, a riverboat accommodating 180 guests in oversized staterooms ranging from 250 to 650 sq. ft. (23-60 m2). Each cabin features private balconies, full-size bathrooms, and generous storage—ideal for longer journeys. Choose from a range of accommodations, including the palatial Grand Suite and dedicated Single Balcony rooms. With its award-winning design, American Serenade blends contemporary aesthetics with natural textures, offering a calm, elegant retreat as you cruise America’s rivers.

Beyond the staterooms, American Serenade invites guests to relax in multiple spacious lounges, enjoy a workout in the fitness center, or stroll the outdoor walking track. A stunning four-story glass atrium offers panoramic views, while elevator access to all decks ensures effortless mobility. Dining is a highlight, with multiple venues serving refined regional cuisine—from Creole classics to Heartland favorites—all prepared fresh daily and enjoyed against a backdrop of flowing river scenery.

Sail from St. Paul to New Orleans on a 16-day epic through the heart of the Mississippi, with stops in culturally rich towns like Hannibal, Memphis, and Natchez. Or opt for a shorter 8-day round trip from New Orleans, exploring the bayou’s soulful rhythms and grand plantations. With expert-guided excursions, engaging onboard lectures, and ever-changing views, each itinerary brings the vibrant spirit and layered history of the Mississippi to life.

Book your next river cruise aboard the American Serenade today.

Choose your departure date

Date

Itinerary

Price

Select

08 Nov

9 Days / 8 Nights

$ 5,275

Select Cabin available

15 Nov

9 Days / 8 Nights

$ 5,275

Select Cabin available

08 Dec

8 Days / 7 Nights

$ 4,650

FULL

14 Dec

8 Days / 7 Nights

$ 4,965

Select Cabin available

20 Dec

8 Days / 7 Nights

Christmas Cruise!

$ 5,775

FULL

26 Dec

8 Days / 7 Nights

$ 5,275

FULL

13 Feb

8 Days / 7 Nights

Up to $1000 OFF! Rates include discounts. Complimentary Airfare Included! Valid for a limited time only.

$ 4,150 Deal %

Select Cabin available

19 Feb

9 Days / 8 Nights

$500 OFF! Rates include discounts. Complimentary Airfare Included! Valid for a limited time only.

$ 4,775 Deal %

Select Cabin available

26 Feb

9 Days / 8 Nights

$ 4,775

Select Cabin available

05 Mar

9 Days / 8 Nights

$500 OFF! Rates include discounts! Complimentary Airfare Included! Valid for a limited time only.

$ 5,135 Deal %

Select Cabin available

12 Mar

9 Days / 8 Nights

Up to $1000 OFF! Rates include discounts. Complimentary Airfare Included! Valid for a limited time only.

$ 5,135 Deal %

Select Cabin available

19 Mar

9 Days / 8 Nights

$500 OFF! Rates include discounts! Complimentary Airfare Included! Valid for a limited time only.

$ 5,135 Deal %

Select Cabin available

Included: VAT, Port Fees, Alcoholic Beverages, Drinking Water, Soft drinks, Tea & Coffee, Welcome Cocktails, Wine with Dinner, Full-Board Meal Plan (All meals), Cabin Towels, Complimentary Toiletries, Deck Towels, Laundry / Pressing Services, WiFi internet.

Book now, pay later: You can easily place your booking online. We will then hold the spaces for you and you can confirm with a payment later.

* Extra fees are shown per person.

Pay by bank transfer or online with

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Boat features

Free Internet
Riverview Cabins
Jacuzzi / Hot Tub
En-Suite bathrooms
Family Cabins
Aircon Cabins
Warm Water Showers
Air Conditioned saloon
Sun Deck
Rooms with Balcony
Non-Smoking Rooms
Charging stations
Indoor Saloon
Laundry Service
Library
Outdoor Dining
Audio & video entertainment
TV in cabins
Observation Deck
BBQ Area
Leisure Deck
Daily housekeeping
Bar

Food & Drinks

Fine Cuisine
Al Fresco Dining
Vegan Options
Vegetarian Options
Free Soft Drinks
Beer available
Wine Available
Welcome Cocktails
Snacks All Day
Buffet style
Western Food
Local Food
Set Menu Dinner

If you have any specific dietary requirements whilst on-board your cruise, you can add this to your special requests on step 2 of the booking form. We advise limiting these requests to religious beliefs or food allergies.